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KMID : 1059520160600020107
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Journal of the Korean Chemical Society
2016 Volume.60 No. 2 p.107 ~ p.110
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Synthesis of Some Novel Thiazolyl - Azetidinone Hybrids
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Ahn Chul-Jin
Hegde Hemant
Shetty Nitinkumar S.
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Abstract
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A new series of hydrazino thiazolyl-2-azetidinone 4(a-i) derivatives were synthesized efficiently using benzylidene hydrazinyl thiazole derivatives 3(a-i). The precursors, benzylidene hydrazinyl thiazoles were prepared by reacting 4- fluoro phenacyl bromide with thiosemicarbazones 2(a-i). All the structures of the synthesized compounds were ascertained by IR, NMR and mass spectral analysis.
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KEYWORD
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Azetidinone, Benzylidene hydrazinyl thiazole, 4-Flouro phenacyl bromide, Thiosemicarbazone
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